programas cribado cancer

Nota bibliográfica cribado c colorrectal 2012-07

Gill MD, Bramble MG, Rees CJ, Lee TJW, Bradburn DM, Mills SJ. Comparison of screen-detected and interval colorectal cancers in the Bowel Cancer Screening Programme. Br J Cancer 2012 Jul 24;107(3):417-21.
Libby G, Brewster DH, McClements PL, Carey FA, Black RJ, Birrell J, et al. The impact of population-based faecal occult blood test screening on colorectal cancer mortality: a matched cohort study. Br J Cancer 2012 Jul 10;107(2):255-9.
Scholefield JH, Moss SM, Mangham CM, Whynes DK, Hardcastle JD. Nottingham trial of faecal occult blood testing for colorectal cancer: a 20-year follow-up. Gut 2012 Jul;61(7):1036-40.  DOI: gutjnl-2011-300774 [pii];10.1136/gutjnl-2011-300774 [doi]  PM:22052062
CONCLUSIONS: Although the reduction in CRC mortality was sustained, further follow-up of the screened population has not shown a significant reduction in the CRC incidence. Moreover, despite the removal of many large adenomas there was no reduction in the incidence of invasive cancer which was independent of sex and site of the tumour

Terhaar sive Droste J, van Turenhout S, Oort F, van der Hulst R, Steeman V, Coblijn U, et al. Faecal immunochemical test accuracy in patients referred for surveillance colonoscopy: a multi-centre cohort study. BMC Gastroenterology 2012;12(1):94.  DOI: 10.1186/1471-230X-12-94
CONCLUSIONS: In once-only FIT sampling before surveillance colonoscopy, 70% of advanced neoplasia were missed. A simulation approach indicates that multiple screening rounds may be more promising in detecting advanced neoplasia and could potentially alleviate endoscopic burden

Young GP, Fraser CG, Halloran SP, Cole S. Guaiac based faecal occult blood testing for colorectal cancer screening: an obsolete strategy? editorial. Gut 2012 Jul;61(7):959-60.  PMC3355341  DOI: gutjnl-2011-301810 [pii];10.1136/gutjnl-2011-301810 [doi]  PM:22345655
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